Nucleic Acid Design - Engineering DNA for Molecular Innovation and Synthetic Biology

Fouad Sabry

Summary

Unlock the potential of nucleic acid design in the rapidly evolving field of DNA nanotechnology. This book is an essential resource for professionals, researchers, students, and enthusiasts eager to explore how nucleic acids can be engineered for groundbreaking applications. Delve into the principles and techniques shaping molecular structures and driving innovation in nanotechnology and synthetic biology.

Chapters Brief Overview:

1: Nucleic acid design – Learn how tailored sequences drive structural formation and nanotechnological functions.

2: Denaturation (biochemistry) – Explore the thermal and chemical factors influencing nucleic acid stability.

3: Nucleic acid structure prediction – Discover computational tools predicting secondary and tertiary formations.

4: Triplestranded DNA – Understand the mechanics and applications of threestranded nucleic acid structures.

5: Base pair – Examine the fundamental interactions forming the genetic code and structural frameworks.

6: DNA nanotechnology – Investigate how DNA is manipulated to create selfassembling nanostructures.

7: Helicase – Study the molecular motors unwinding DNA for replication and repair processes.

8: ViennaRNA Package – Utilize computational software for RNA secondary structure predictions and analysis.

9: Nucleic acid tertiary structure – Analyze the higherorder folding principles essential for function.

10: Nucleic acid thermodynamics – Understand the energetic principles governing nucleic acid stability.

11: RNA origami – Explore the art of folding RNA into intricate, functional nanostructures.

12: Spherical nucleic acid – Investigate nanoscale spherical architectures with biomedical applications.

13: Holliday junction – Delve into the structural dynamics of recombination intermediates.

14: Hoogsteen base pair – Examine alternative hydrogen bonding patterns and their biological significance.

15: Nucleic acid secondary structure – Learn how sequence dictates hairpins, loops, and other formations.

16: Nucleic acid double helix – Revisit the canonical structure that underpins genetic information.

17: Nucleic acid structure – Analyze the interplay of primary, secondary, and tertiary formations.

18: Peptide nucleic acid – Discover synthetic nucleic acid analogs with unique stability and binding properties.

19: Noncanonical base pairing – Investigate unconventional interactions that expand structural complexity.

20: DNA origami – Learn how DNA strands are folded into programmable nanostructures.

21: TectoRNA – Examine modular RNA structures enabling complex selfassembly and function.

Mastering nucleic acid design opens doors to innovations in medicine, nanotechnology, and synthetic biology. This book provides a structured, indepth guide tailored to learners and experts alike, offering knowledge that far outweighs its cost. Expand your expertise and explore the limitless potential of DNA nanotechnology today.

Available since: 03/14/2025.

Print length: 281 pages.

Science & Technology

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