RNA Origami - Engineering Self Assembling Structures at the Nanoscale

Fouad Sabry

Summary

Unlock the revolutionary potential of RNA origami in the rapidly evolving field of DNA nanotechnology. This book provides a comprehensive yet accessible exploration of how RNA structures can be rationally designed for applications in molecular engineering, nanomedicine, and synthetic biology. Whether you're a researcher, student, or enthusiast, this book offers critical insights into the next frontier of biomolecular design.

Chapters Brief Overview:

1: RNA origami – Introduces the concept of RNA origami and its significance in nanotechnology.

2: Native state – Examines RNA folding and stability in its natural biological environment.

3: Biomolecular structure – Discusses fundamental principles governing the architecture of biomolecules.

4: Holliday junction – Explores this key nucleic acid structure and its role in genetic recombination.

5: Nucleic acid quaternary structure – Covers higherorder structural organization in nucleic acids.

6: Spherical nucleic acid – Details how nucleic acids form spherical nanostructures with novel applications.

7: Protein biosynthesis – Explains RNA’s role in guiding the synthesis of proteins.

8: Biomolecule – Provides insights into the structure and function of biomolecules in nanotechnology.

9: Nanoruler – Introduces nanorulers and their application in precise molecular measurements.

10: Nucleic acid tertiary structure – Analyzes the intricate folding patterns of nucleic acids.

11: TectoRNA – Highlights modular RNA units used for constructing complex nanostructures.

12: Nucleic acid design – Discusses principles and strategies for designing functional RNA and DNA.

13: Molecular models of DNA – Explores computational and physical models of DNA structures.

14: Nucleic acid structure – Examines structural variations in DNA and RNA molecules.

15: DNA – Provides a foundational understanding of DNA’s role in biological and synthetic systems.

16: Nucleic acid secondary structure – Explores base pairing and folding patterns critical for RNA function.

17: Base pair – Discusses fundamental basepairing rules and their influence on nucleic acid stability.

18: History of RNA biology – Chronicles key discoveries shaping modern RNA research.

19: DNA nanotechnology – Explains how DNA is engineered for nanoscale applications.

20: DNA origami – Introduces the concept of folding DNA into precise nanoscale shapes.

21: Noncanonical base pairing – Explores alternative basepairing interactions in RNA and DNA structures.

With a clear structure and indepth exploration, this book equips professionals, students, and hobbyists with the knowledge to navigate the exciting intersection of RNA origami and DNA nanotechnology. By bridging molecular biology and engineering, this resource ensures readers stay ahead in an era where synthetic biology is reshaping science and technology.

Available since: 03/06/2025.

Print length: 305 pages.

Science & Technology

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