Nanoparticles Brain Drug Delivery - Advancements in Targeted Treatment for Neurological Disorders
Fouad Sabry
Publisher: One Billion Knowledgeable
Summary
Nanoparticles for drug delivery to the brain-This chapter introduces the role of nanoparticles in enhancing brain drug delivery, emphasizing their ability to cross the bloodbrain barrier Blood–spinal cord barrier-Explore the challenges and solutions in delivering drugs across the blood–spinal cord barrier using nanoparticle technology Lipidbased nanoparticle-Discusses lipidbased nanoparticles' advantages in drug delivery, focusing on their biocompatibility and efficiency in brain targeting RNAi nanoparticles to target cancer-Examines the use of RNA interference nanoparticles to target cancer cells in the brain, offering a promising therapeutic approach Nanocapsule-Details the role of nanocapsules in drug delivery, with a focus on their ability to encapsulate and protect drugs for controlled release Vectors in gene therapy-Looks at the importance of nanoparticles as gene delivery vectors, enhancing the precision of gene therapies for neurological conditions Targeted drug delivery-Explores various targeting mechanisms used in nanoparticle drug delivery systems to improve drug efficacy and reduce side effects Intranasal drug delivery-Investigates the effectiveness of intranasal administration of nanoparticles for delivering drugs directly to the brain Nanoparticle–biomolecule conjugate-Focuses on the conjugation of nanoparticles with biomolecules to enhance drug targeting and effectiveness Drug delivery to the brain-Reviews various methods and technologies used to deliver therapeutic agents directly to the brain, highlighting nanoparticles' role Nanoparticle drug delivery-A comprehensive review of nanoparticle drug delivery systems, exploring their applications, challenges, and future potential Nanoneuroscience-Delve into the emerging field of nanoneuroscience, where nanoparticles are used to study and treat brain diseases and disorders Immunoliposome therapy-Examines the use of immunoliposomes, a nanoparticlebased system, in delivering drugs and immune therapies to the brain Magnetic nanoparticles in drug delivery-Discusses the role of magnetic nanoparticles in targeted drug delivery, including their ability to be directed to specific areas of the brain Microbubble-Investigates how microbubbles are used in conjunction with nanoparticles for noninvasive drug delivery to the brain, enhancing treatment precision Nanogel-Looks into the potential of nanogels in drug delivery, focusing on their ability to provide controlled release and targeted treatment for brain disorders Blood–brain barrier-Explores advanced strategies for overcoming the bloodbrain barrier, a major challenge in drug delivery to the brain Cytokine delivery systems-Analyzes how nanoparticles can be used to deliver cytokines to the brain, offering new avenues for treating neuroinflammatory diseases Cationic liposome-Discusses cationic liposomes in drug delivery, focusing on their potential to efficiently deliver therapeutic agents to the brain Focused ultrasound for intracranial drug delivery-Investigates the combination of focused ultrasound and nanoparticles in enhancing drug delivery to the brain Transcytosis-This chapter looks at how nanoparticles can exploit transcytosis to bypass biological barriers and deliver drugs directly to the brain
