Aptamer - Exploring the Potential of Nucleic Acid Based Molecular Recognition

Fouad Sabry

Summary

In the realm of Molecular Machines, aptamers play a crucial role in advancing biotechnology, diagnostics, and therapeutics. This book explores the fascinating world of aptamers, their development, and their application in scientific innovations. A mustread for professionals, students, and enthusiasts alike, it offers a comprehensive guide that connects molecular science to realworld applications.

Chapters Brief Overview:

1: Aptamer: Learn about the structure, function, and significance of aptamers in molecular machines.

2: Systematic evolution of ligands by exponential enrichment: Explore how SELEX technology revolutionized aptamer development.

3: Xeno nucleic acid: Understand the role of xeno nucleic acids in creating more stable aptamers.

4: Peptide nucleic acid: Discover how peptide nucleic acids enhance aptamer function and stability.

5: Fluorescent tag: Explore how fluorescent tags are used to track and study aptamer interactions.

6: Affinity chromatography: Dive into the technique of affinity chromatography in purifying aptamers.

7: MRNA display: Understand the application of mRNA display for aptamer selection and screening.

8: Deoxyribozyme: Learn about the catalytic properties of deoxyribozymes in molecular machines.

9: Protein microarray: Discover how protein microarrays are used to study aptamerprotein interactions.

10: LRibonucleic acid aptamer: Understand the potential of LRNA aptamers in therapeutic applications.

11: Digoxigenin: Explore the use of digoxigenin as a molecular tag in aptamerbased assays.

12: DNAbinding protein: Learn about DNAbinding proteins and their interaction with aptamers.

13: Phage display: Examine how phage display is utilized for aptamer selection and characterization.

14: Affimer: Discover the new class of affinity proteins known as Affimers and their similarities to aptamers.

15: Synthetic antibody: Understand synthetic antibodies and their potential to replace traditional antibodies in diagnostics.

16: DNAencoded chemical library: Learn about DNAencoded chemical libraries and their role in aptamer discovery.

17: Optimer ligand: Discover the potential of Optimer ligands in enhancing aptamer function.

18: RNA therapeutics: Understand how aptamers are utilized in RNAbased therapeutic applications.

19: Biosensor: Explore the use of aptamers in biosensors for rapid diagnostics and environmental monitoring.

20: Threose nucleic acid: Learn about threose nucleic acid and its potential for creating stable aptamers.

21: Electrochemical aptamerbased biosensors: Understand the working principles and applications of electrochemical aptamer biosensors.

This book offers an essential guide for those in the field of molecular machines, providing insights into the many roles aptamers play. Through detailed explanations and practical examples, it shows how aptamers are a vital component in the rapidly advancing field of biotechnology. Whether you're a student, professional, or enthusiast, this book will deepen your understanding and provide valuable knowledge that goes beyond the theoretical to the applied.

Available since: 03/10/2025.

Print length: 231 pages.

Science & Technology

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