Weitere Bücher, die Sie mögen werden

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  The Shocking Truth about...

  Zoey Fraisers

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  Pharmaceutical trials are essential to the development of new drugs and treatments, providing the necessary data to ensure they are safe and effective for public use. These trials have evolved over centuries, from rudimentary experiments to the sophisticated, multi-phase studies we see today. They are the cornerstone of modern medicine, influencing the drugs that populate our pharmacies and hospitals. However, the process is not without its flaws, and the history of pharmaceutical trials is marked by ethical concerns, controversy, and a complex relationship between researchers, pharmaceutical companies, and patients. 
    
  The primary goal of pharmaceutical trials is to test new drugs and therapies on human participants to gather data on their safety, efficacy, and potential side effects. These trials follow a strict protocol, designed to minimize risks while maximizing the quality of the data collected. The process typically begins with preclinical testing in laboratories, followed by clinical trials involving human subjects. These trials are divided into several phases, each designed to answer different scientific questions. From small-scale phase I trials to large-scale phase III studies, the data gathered at each stage is critical in determining whether a drug is ready for approval by regulatory authorities. 
    
  However, the path from laboratory to pharmacy shelves is not always smooth. The influence of pharmaceutical companies looms large over clinical trials, as they fund many studies and are often the driving force behind research agendas. While their involvement has led to groundbreaking advancements in medicine, it has also raised concerns about conflicts of interest and the integrity of trial data. In some cases, financial pressures have led to the manipulation or suppression of results that could impact a drug’s approval.

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  Earthopolis - A Biography of Our...

  Carl H. Nightingale

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  This is a biography of Earthopolis, the only Urban Planet we know of. It is a history of how cities gave humans immense power over Earth, for good and for ill. Carl Nightingale takes readers on a sweeping six-continent, six-millennium tour of the world’s cities, culminating in the last 250 years, when we vastly accelerated our planetary realms of action, habitat, and impact, courting dangerous new consequences and opening prospects for new hope. In Earthopolis we peek into our cities’ homes, neighborhoods, streets, shops, eating houses, squares, marketplaces, religious sites, schools, universities, offices, monuments, docklands, and airports to discover connections between small spaces and the largest things we have built. The book exposes the Urban Planet’s deep inequalities of power, wealth, access to knowledge, class, race, gender, sexuality, religion, and nation. It asks us to draw on the most just and democratic moments of Earthopolis’s past to rescue its future.

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  Machine learning

  Bright Mills

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  Machine Learning (ML) is a subset of Artificial Intelligence that empowers systems to learn from data and make decisions or predictions without being explicitly programmed. It represents a major shift from traditional rule-based programming to systems that adapt and improve over time. This comprehensive guide delves into the theoretical foundations, types, algorithms, tools, applications, challenges, and the future of Machine Learning. It covers supervised, unsupervised, semi-supervised, and reinforcement learning in detail, explains key techniques such as neural networks, decision trees, support vector machines, and deep learning, and explores real-world applications across domains like healthcare, finance, security, and robotics. Ethical concerns, bias in AI, explainability, and interpretability are also discussed, offering a well-rounded understanding of the state and direction of Machine Learning.

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  Black Holes and Beyond - The...

  Dirk Fallon

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  Black holes are some of the most fascinating and mysterious objects in the universe. These regions of space are so dense that their gravitational pull is strong enough to prevent anything, even light, from escaping. The term "black hole" was first coined by physicist John Archibald Wheeler in 1967, though the concept dates back to the early 20th century, when Albert Einstein's theory of general relativity suggested that objects could collapse into singularities, points of infinite density. A black hole is the result of such a collapse, where a star's mass is concentrated in an infinitely small space. 
  At the heart of a black hole is the singularity, surrounded by a boundary known as the event horizon. The event horizon marks the point beyond which nothing can escape the black hole’s gravitational influence. This includes not only matter but also radiation, which is why black holes appear "black." Despite their invisibility, black holes are detectable through their interactions with surrounding matter, such as the accretion of gas and dust that emits detectable radiation. 
  The formation of a black hole typically begins when a massive star exhausts its nuclear fuel. Without the outward pressure from nuclear fusion to counterbalance gravity, the core of the star collapses under its own weight. If the star is massive enough, this collapse can continue, compressing the core into a singularity. The outer layers of the star are expelled in a supernova explosion, and the remaining core becomes a black hole.

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  Living Medicine - Don Thomas...

  Dr. Fred Appelbaum

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  A sweeping biography of the visionary behind bone marrow transplantation and the story of the diseases cured by Don Thomas's discovery. In the last half of the twentieth century, Thomas himself discovered a cure for every marrow-based disease—like leukemia, lymphoma, and sickle-cell anemia—forever changing treatment for some of the deadliest illnesses. His feats were extraordinary, earning him a Nobel Prize, and the cascade of treatments he inspired have reshaped and will continue to reshape the practice of clinical medicine. Yet no one has ever written Thomas’s courageous story. Dr. Frederick R. Appelbaum, a member of Thomas’s research team, does so for the first time in Living Medicine: Don Thomas, Marrow Transplantation, and the Cell Therapy Revolution. Bone marrow transplantation has now saved over a million lives, but when Thomas first had the idea, he was met with disbelief by the scientific community. Appelbaum, informed by decades in the field and personal connection with Thomas, tells us the secrets to Thomas’s success: his unique characteristics, how he created an effective team of researchers, and how he overcame the technical obstacles of marrow transplantation. Appelbaum tells a bigger story, too, of the scientific and societal implications of this achievement, which are critical for scientific and lay readers alike so that we all might be better informed of how far our medical progress has come and will go.

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  CIA Gateway Process: Time...

  Meditative Hearts

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  The CIA's Gateway Process is an intriguing exploration into the depths of human consciousness and its untapped potential. Developed during the Cold War era, this program utilizes advanced audio technologies to synchronize brainwave frequencies, enabling participants to access altered states of awareness. Through a combination of binaural beats, guided meditation, and specific breathing techniques, individuals can experience Out-of-Body Experiences (OBE), astral projection, lucid dreaming, and even the theoretical possibility of time travel. 
  The process begins with the induction of a deeply relaxed state, allowing the mind to transcend its usual limitations. As brainwave frequencies align, participants report experiencing heightened states of consciousness, where the boundaries of physical reality become permeable. This state facilitates profound insights, enhanced creativity, and the ability to explore dimensions beyond the ordinary waking experience. 
  Astral projection and OBEs involve the sensation of leaving one's physical body and traveling in a non-physical form to distant locations or other realms of existence. Lucid dreaming, another key aspect of the Gateway Process, empowers individuals to consciously navigate and manipulate their dream environments. 
  The Gateway Process represents a unique fusion of scientific inquiry and metaphysical exploration, offering a groundbreaking journey into the mysteries of the mind and the universe. It challenges conventional perceptions of reality, opening doors to extraordinary experiences and profound personal transformation.

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