PH Responsive Tumor Targeted Drug Delivery - Advancing Precision in Cancer Therapy Through Nanomedicine
Fouad Sabry
Maison d'édition: One Billion Knowledgeable
Synopsis
PHresponsive tumortargeted drug delivery-The opening chapter introduces the principles of pHresponsive drug delivery systems, focusing on their application in targeting tumor cells with greater precision Ligandtargeted liposome-This chapter explores the use of ligandtargeted liposomes in delivering drugs to specific tumor sites, offering an efficient strategy for selective drug release Pullulan bioconjugate-Delving into the innovative use of pullulan bioconjugates, this chapter highlights their role in enhancing the stability and targeting abilities of drug delivery systems Drug carrier-An overview of drug carriers and their mechanisms, detailing how these carriers improve the bioavailability and therapeutic efficacy of anticancer drugs Ultrasoundtriggered drug delivery using stimuliresponsive hydrogels-This chapter presents the integration of ultrasound with stimuliresponsive hydrogels, a groundbreaking method to trigger localized drug release at tumor sites Nanogel-Focuses on nanogels, which are gaining attention as advanced delivery vehicles due to their versatility in drug encapsulation and controlled release Nanocarrier-Explores various types of nanocarriers, detailing their potential in drug delivery, enhancing the targeting and bioavailability of therapeutic agents Intravesical drug delivery-Discusses the emerging strategy of intravesical drug delivery, focusing on how it improves local cancer treatment by delivering drugs directly to the bladder Nanoparticle drug delivery-This chapter reviews the diverse applications of nanoparticles as carriers for targeted drug delivery, emphasizing their potential in improving cancer therapies Reductionsensitive nanoparticles-Examines nanoparticles that respond to reducing environments within tumors, allowing for controlled drug release at precise locations Microbubble-Discusses microbubbles, their role in enhancing drug delivery when combined with ultrasound, and their applications in cancer therapy Stimuliresponsive drug delivery systems-An exploration of various stimuliresponsive systems, including those sensitive to pH, temperature, and light, in optimizing drug delivery efficiency Aldoxorubicin-This chapter details the use of aldoxorubicin, a drug conjugated to a pHsensitive linker, for targeted drug delivery in cancer treatment Intranasal drug delivery-Focuses on the potential of intranasal drug delivery as a noninvasive method for targeting tumors, with a special emphasis on brain cancer therapies Dextran drug delivery systems-Explores dextran as a biocompatible and versatile polymer for drug delivery, particularly in cancer therapy Arginylglycylaspartic acid-An indepth discussion of Arginylglycylaspartic acid (RGD) peptides and their applications in targeting tumors, enhancing delivery efficiency Sonodynamic therapy-Reviews sonodynamic therapy, a promising technique combining ultrasound and photosensitive agents for targeted drug delivery in cancer treatment Anthracycline-Discusses the use of anthracyclines in combination with nanocarriers, improving their therapeutic effect by increasing targeted delivery Magnetic nanoparticles in drug delivery-This chapter examines the application of magnetic nanoparticles in drug delivery, focusing on their ability to concentrate therapeutic agents at tumor sites using magnetic fields Immunoliposome therapy-Explores immunoliposomes, combining liposome technology with immune targeting to deliver cancer drugs directly to tumor cells
