Peptide Nucleic Acid - Innovative Approaches to Molecular Architecture and Nanostructure Design

Fouad Sabry

Beschreibung

Discover the fascinating world of peptide nucleic acids and their profound implications in the field of DNA origami. "Peptide Nucleic Acid" provides comprehensive insights into this groundbreaking subject, blending both theoretical and practical aspects of nucleic acid science. Whether you're a professional in the field, an undergraduate or graduate student, or simply an enthusiast, this book offers invaluable knowledge on the latest advances in nucleic acid analogues and their applications.

Chapters Brief Overview:

1: Peptide nucleic acid: An introduction to the structure and function of peptide nucleic acids (PNAs) in genetic research.

2: Sequencecontrolled polymer: Explores the synthesis and significance of sequencecontrolled polymers in DNA origami applications.

3: Ribozyme: Focuses on the role of ribozymes in catalyzing RNA reactions, expanding the scope of nucleic acidbased technologies.

4: Oligonucleotide: Examines the properties and uses of oligonucleotides in diagnostics and therapeutics.

5: Nucleic acid analogue: Analyzes the properties of nucleic acid analogues, enhancing stability and specificity in genetic manipulation.

6: Morpholino: Discusses morpholino oligos as therapeutic agents and their applications in gene silencing.

7: Threose nucleic acid: Introduces threose nucleic acids and their potential for creating novel nucleic acidbased structures.

8: Polyelectrolyte theory of the gene: Highlights the relationship between genes and their interaction with polyelectrolyte molecules.

9: Nucleic acid: Provides a detailed overview of the chemical properties and functions of nucleic acids in molecular biology.

10: Cellpenetrating peptide: Investigates cellpenetrating peptides as tools for drug delivery and gene therapy.

11: Intracellular delivery: Examines the methods and technologies for efficient intracellular delivery of nucleic acidbased drugs.

12: MRNA display: Focuses on the technique of mRNA display for the selection of peptides and proteins with specific functions.

13: Triplestranded DNA: Delves into the mechanics and applications of triplestranded DNA in molecular recognition.

14: Locked nucleic acid: Explores locked nucleic acids and their impact on the stability and function of genetic sequences.

15: Xeno nucleic acid: Introduces xeno nucleic acids as a class of synthetic molecules for biotechnological applications.

16: Aptamer: Discusses aptamers and their potential to replace antibodies in diagnostics and therapeutics.

17: Nucleic acid secondary structure: Focuses on the role of secondary structures in nucleic acid functionality and stability.

18: RNA world: Examines the RNA world hypothesis, exploring the origin of life and its implications for modern biotechnology.

19: Diamino acid: Investigates diamino acids and their applications in constructing new types of biomolecular systems.

20: XIST: Discusses XIST RNA and its regulatory role in X chromosome inactivation.

21: Systematic evolution of ligands by exponential enrichment: Explores SELEX, a powerful method for selecting aptamers with high affinity and specificity.

This book connects the dots between cuttingedge research and realworld applications, providing readers with a deep understanding of the science behind DNA origami. Its interdisciplinary approach makes it a mustread for anyone seeking to explore the potential of peptide nucleic acids and their role in biotechnology.

Verfügbar seit: 08.03.2025.

Drucklänge: 305 Seiten.

Wissenschaft & Technologie

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