Intracellular Delivery - Advancements in Targeted Therapy for Nanomedicine Applications

Fouad Sabry

Beschreibung

"Intracellular Delivery" is a groundbreaking work that explores the vital techniques and methodologies used in the field of nanobiotechnology, with a focus on the delivery of biological materials into living cells. This book will provide professionals, researchers, and students with a detailed understanding of cuttingedge intracellular delivery methods, which are essential for advancements in gene therapy, vaccine development, and RNA therapeutics. As nanobiotechnology continues to revolutionize medicine, this resource is indispensable for anyone looking to stay ahead in this rapidly evolving field.

Chapters Brief Overview:

1: Intracellular delivery: An introduction to the importance of delivering substances into cells for therapeutic purposes.

2: Magnetassisted transfection: Overview of using magnetic fields to enhance gene delivery into cells.

3: Transfection: Discussion of various methods used to transfer genetic material into cells.

4: Lentivirus: Exploration of how lentivirus vectors are used for stable gene delivery in cells.

5: Electroporation: Explanation of how electric pulses facilitate the transfer of DNA into cells.

6: Nanoinjection: The role of nanotechnology in delivering materials directly into cells using nanosized tools.

7: Cationic liposome: Overview of liposomes that can facilitate the efficient transport of genetic material into cells.

8: Genetic vaccine: Insights into how intracellular delivery aids the development of genetic vaccines.

9: RNA therapeutics: Discussion on the role of RNAbased therapies and the importance of efficient delivery systems.

10: Cellpenetrating peptide: Examination of peptides that can penetrate cell membranes to deliver therapeutic agents.

11: Sonoporation: Use of ultrasound waves to open cell membranes, allowing for the entry of therapeutic agents.

12: Genetic engineering techniques: The application of intracellular delivery for advancing genetic engineering research.

13: Hydrodynamic delivery: Overview of using pressuredriven systems to deliver substances into cells.

14: Vectors in gene therapy: The role of viral and nonviral vectors in improving gene therapy outcomes.

15: Gene delivery: A comprehensive look at the various strategies for delivering genes into target cells.

16: DNA construct: Examination of the design and use of DNA constructs for gene delivery into cells.

17: Tissue nanotransfection: Cuttingedge research into tissuespecific delivery of genetic material for therapeutic purposes.

18: MRNA vaccine: Insights into the design and delivery of mRNA vaccines for precision medicine.

19: Small interfering RNA: Explanation of how siRNA is used in gene silencing and therapeutic interventions.

20: Exogenous DNA: The process of introducing foreign DNA into cells to study genetic expression and function.

21: Magnetofection: A discussion of using magnetic fields in combination with viral vectors to enhance gene delivery.

This book will equip you with the knowledge needed to grasp the complexities of intracellular delivery, offering practical insights into the techniques that can advance healthcare, biomedical research, and drug development. Whether you are a student, professional, or enthusiast, "Intracellular Delivery" will help you deepen your understanding of nanobiotechnology’s critical role in modern science.

Verfügbar seit: 10.03.2025.

Drucklänge: 248 Seiten.

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