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Synopsis

Medicinal chemistry is a specialized field at the intersection of chemistry, biology, and pharmacology, focused on the design, development, and synthesis of biologically active compounds for therapeutic use. It plays a vital role in the pharmaceutical industry, guiding the process by which new drugs are discovered and optimized to treat a wide range of diseases. By understanding the molecular basis of disease and the interaction between drugs and biological targets, medicinal chemists are able to develop compounds with improved efficacy, selectivity, and safety. 
The origins of medicinal chemistry can be traced back to ancient times, where natural products such as plant extracts were used for healing purposes. However, it was not until the 19th and 20th centuries that the discipline began to evolve scientifically, with the isolation of active compounds and the development of synthetic drugs. Landmark discoveries, such as the synthesis of aspirin, sulfonamides, and penicillin, paved the way for modern drug design and the systematic study of drug behavior at the molecular level. 
Today, medicinal chemistry is recognized as a key component in the drug discovery pipeline. It involves not only the synthesis of new chemical entities but also the study of their pharmacokinetic and pharmacodynamic properties. Medicinal chemists must consider how a compound is absorbed, distributed, metabolized, and excreted by the body, as well as how it interacts with its intended target. This requires a deep understanding of chemical reactivity, molecular interactions, and biological systems.

Durée: environ 2 heures (01:57:59)
Date de publication: 17/04/2025; Unabridged; Copyright Year: — Copyright Statment: —

• Business et Économie
• Science et Technologie